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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5650852aa4b4b69c272eb9a44b41d7e56ea4ca7c5e54ab036f9888ba727b417' 
  AND token = '9lfrZZzhbOWaCdcu2P2VFzHPign1EHCN5hGVodav/Ns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}