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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a36146b8ad3e663f06f6d8e26d1942975cf73101dd7100b8e7db4dfe1f6072f' 
  AND token = 'wIBzgxUbjm7smSxgY++19cJg4qrfG87YAqOietIgyHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}