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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c51b365445234189e09a410e6dbe628de7a54e29278cffe6f5b88455e8a1691' 
  AND token = 'ZS2NGXhxrAmeCGBdb+XoXHPiF5ILEykVtcdDv9R7dNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}