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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6701258ec8828149d3ae4c7d72c1108c17a89187a48fdc69905be63e40387b9d' 
  AND token = '25jW4YyrVklOflYj7jxeyfD6N37XJnWZjWH3rT9QuZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}