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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20df022b44333a51b2177616fa3580231b049f28d6b7cf831463d056813bece1' 
  AND token = 'NcEm8x6xDpGS9SNMyvPnYzD2L/2tRnWTVhLHej0KOvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}