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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bd5a0b735610509a7cf70f9b22cfafffd14ffd44b313463d95a2a473b27abda' 
  AND token = 'tcAzWVSzDHRI+49IpqgTUexner4fNf/kR0twYEBFcWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}