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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d554b7a3227cb795ce642caed0e792b05c610e3bd518bcadc07a724225fc556' 
  AND token = 'fxJNX3J5Jc2gk8131bMrEE4puIG7CiQ3bBY5e1YNkuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}