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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bd9a1a4b60e5261cb511105d903b90c4d0b56d6c387a3e6769df2e7fc012b44' 
  AND token = 'HeknrZlWY0mLPpkBxuhyZfIhwSgERpNZJpRY+9nazok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}