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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c50a5d89495d94f538b955130495747471f688fd67504a2912d27603c87c2462' 
  AND token = 'awQDdSac/Z7odriV8su78xID5T5Up6nK1nyUNoTh7Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}