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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe0121f834d9a8e9ac048b1f9554d42cbf633e81660abcc040827b43a9e13d6' 
  AND token = 'Rexrn87RN04SXOeZAX4DzKr72VDlci+i5P9oSa+XCAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}