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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0d3b9e236d10640791e59df5ed52cee61e12a7cb5e93bbf9b564e7a160f36d' 
  AND token = 't5f3UuLHFpMOKz0sdMaCvXKf5wH2uJBzM8aPVEHDOl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}