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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd6a26462fff164b4dc6c6f5c106d79c3019de26b6edb35323d8f63ac70c347a' 
  AND token = 'A0LxRQgaIPGEN0p+mIIdcn+Sf9l7rvVp76W1h27JAPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}