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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7a28003f5b18899371cc1645da3fca211afbe7e3b88076a195324d0c53eafa3' 
  AND token = 'i5DLPAk7+uq1nP1m/Q95pXw5FZ5lvSt1P73f/hpBqC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}