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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51fe6f00157b607521f647f159d1bdc0352bfcc7f241223ad98e324ef97bc32d' 
  AND token = '+YDt7XuCGWeN7U/C4gu4vWuDdY517zd/IPS2Oia32zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}