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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a37d0c55518b411855424fcb055bf986171f3ccaedd86a3d5a48da81394022cc' 
  AND token = 'UQn+6DTj+UD1L2R9kaWYYrCF6+gwOxtN1/nEyZmFp8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}