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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f10933e321655b7c37afb74305b0d5a18c1c5a21bf63c890d737166ce4a4236' 
  AND token = 'oN5QwkpPqx8QWQXLXAt/egAHO1h3Mm9Io3CZ2M5zp/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}