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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a86a01cd50a631a504b2dd8408fe3cae3745efafae2f26960d9933bc41f52848' 
  AND token = 'Oi0TUv3xQ1FHFTuHGisp42h1uMtot4F8KwC2WlCOic4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}