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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d1ae178748b0948b22a60f67e493b69f795d4e86dc0c520868209f7c4084f20' 
  AND token = 'XbK5dG7X8nYRPaRcyTK7hXmGLgfcOSBMzgQyGa0KTm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}