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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d3aefb3d049ff7669b4ff590ad73839f325cf678067dbf42cb5d51e4f39f83c' 
  AND token = 'mDPlSJ6VgItceLG4L+V9ESVsCotfhGmftRBrj6rvWV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}