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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9146ef8a613648e028a80cc83c929c3befc7d5b147611cc01a87307032ac17' 
  AND token = 'KBYvltoTjGaOASxH+bQbbD6p+gMfhh/hx+dKdyCCyhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}