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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a536cb654562e8ca6fb8311576089120a0f48a161684639640b18b0b0af933' 
  AND token = 'oM+gHVAK9qQO1kQ1+MiMmjqqB+znBDSv2n5RW3qk2RA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}