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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ad91d716f17d2706d09fc8ad3777822c4fffc6835d79a90f6bd2a56d06a039b' 
  AND token = 'Y9SQLSSsbC5Q+mRnRMcvy4ECBVkIm6DLKM3BkZluqPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}