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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b0ffd1eeacac1bfdf51a77e618d5b90f0e6fe31fe061af50d0e3e8d483b46f' 
  AND token = 'uAlS9AZh7ecruD8ogFqbhAxxASxx3t3vCS+Sq6cuj4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}