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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e44c01c5cc07101a71e7afc95f57b0a59877e6a038f494221e79b6ca688c950' 
  AND token = 'Sx6pSpvRYF3+MqJb+fzjgFoS3T4UF54D8fUk7NOGyvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}