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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec22858990162ae5273b6164b9ba798441e7dfd3da0bf62d9c6dda16f2cb016' 
  AND token = 'cw+D7zBAs3thutfQ/XI7VCp6DEhS+uY1m+GhSnXemEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}