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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2208189d368c0416040a55b37b0eb3837aaee9a6d144825202d11899e8620077' 
  AND token = 'TYXqjcRdtMGVWPIyCFTTOe83FRsJ/q9/uinaJFoS6hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}