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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eff0c6a8dcd8c101871c5419af87b31d7e7339a018951c464266d742db1af0fe' 
  AND token = 'VfXdBzj7TLT+Pubs8T6hKI5RRVQDkJQBAzeU8gcT8dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}