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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e14a04878863c5621dd2f32711a97e4cb2eec6dde49d4bfcfb8a8e185262aa9' 
  AND token = 'hS+vgB5t0EXnMpJd4GEZsc8obu5iZV8qu3Zd5Oczj5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}