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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3176dee19c29693bfc521d5e311663894ed3dce93dd8c65a6a7846e50d2c1e51' 
  AND token = 'voxgMunAQCGiRZwSzt624GimrM8r93UDjlp3BqmHlTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}