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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68f3fb61759cbf642a563eda2ce1948425e408a4249ee7dfcaf647a4874c3866' 
  AND token = '+qS9+Tg1ngqM/lrUdQ5lOsD3ttKAtNzg8tqCvy1wn/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}