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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53fb83d94f41ec92eb3cc70517a71c2bfe8e76ec37f811aa7e5d442edbec4e25' 
  AND token = 'BTgxZBxGNhNa7zCD4sZO48e4iEZJ8xQ3b7zxjaHr8fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}