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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b66bb6b5808d6418ec011ee02daffe014cbc4561e287f4928427cbd1edce15e' 
  AND token = 'hEL8MW02oL3VMJBFA+LtIc7tcf+9+ItUQVu+/gZ2WBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}