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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e293a9f6cbf272b99d53bb15303a98324e38a0db782cea2291aadeac1cfbfb05' 
  AND token = 'oyHBozivnpuOnmr1s83qQ4QtIQzLXoFbNUaPpJ6ZFlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}