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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '900cf99541bb9e7ac6713025afa2c77bf3e8682f65b0c3fec28b58e22a0e02e6' 
  AND token = 'GCVx5Wynx+k2axAcPY/qUgpAIDvJzZqN+qlU3yXsT4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}