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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a334f5e87b51575179b0c586f8579449492fd28539137fc4947cc06611c5e1a' 
  AND token = 'jAyiT9XcmDGa2idaYmYqFbX69BpTEwwgM7NlCwvuIY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}