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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03b313c5ac0c2054fcdf335bcad8f6183d145f2434220101224da276a4430201' 
  AND token = '/vzZWEfkENcntn9PODA92k2To33MxkLlK25/LxIMY3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}