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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6fbe32fa051e8961f7395d47a4cc86ed0f67ebad3eeeb479d752f728deb777a' 
  AND token = 'Wvsx5B09+/zTwTx7VtLzB0EkYUTH6pU0O1GH4ioQAsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}