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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389d631e30784179b1255f0b25a38adc01720d6ffe361e8d61d2e4918a1ef1ec' 
  AND token = 'PNcJXRNJaeX++fAbpaj0bwFSAW7j5gdty+LUMvidyyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}