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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc188dd2611c3551003261ffb561406f68f2d0004602f5f733d7a05b610868ce' 
  AND token = 'QW1uQicmlNqXRud1XFwNry6hbsAcaD0SeKB+f+jkL9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}