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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cdd945ab703a846619f1066dab6949301abb7d0d9a66e115140dc32c11d1d29' 
  AND token = 'TKfUTu6488ePFR+5Du/4e54xMM8szOpJq5t6C/UCKRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}