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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec0507471e1cbad8567288e11b53b7d72f9099022b711b05a26a4a1dc3d8319a' 
  AND token = 'hcV/E4eLoD6xWg6CsFXc84tGys4ArUdwPcM2ws0e1mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}