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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a7f69377f443df145755cd7467aa752d57a0cb43a65b5c43841dce2e0c135d7' 
  AND token = 'VPtoGGEDlkjmN3wrHE5yYAl335yxfo+BfHaGd4ZG7nU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}