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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf7a1e9c87e90989a23168524a7dbbbbcc777f4b0acbd908749f97e97bb244ab' 
  AND token = 'O3mzt+kp6wsaQhRltVAAB83IhLkBAPjA8CAPYeeAGTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}