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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdc01214cb322a6a44a935ae6508b4444ad9e50b42165b85d4f4bb8e7598b1b8' 
  AND token = 'jB46Qjej1yPAOBq+IoZqQA2fCwfO/7KXBDRI4Ai74Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}