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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acffeb2da2a541ad3f640b318794d6809c5fa9349bbaa66d396a7a7a368707c4' 
  AND token = 'IqmsxVjGjS8sBfrbNce4FNseKqqhmNVph24dE5NFXgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}