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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5d0a971dcd94e95ac7855bdc2198f78e719500d7cb79e51771467ada03f5474' 
  AND token = 'VO1ipCZktXjk2V1wLao6NXHiCF4mDW1AYcUHKTltijA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}