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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4780ee59d13915c60a562decb4aabc12320573a3d5a5b8da0b81d829fe5f40b4' 
  AND token = 'gDaZgAEAyfp8JCpWyCxsBm0xRPuw7P2IFFs1UEZ4h7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}