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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143c101eae091cc1d10f23b7bc5d7d65646e08fdc3f2bc873ac31520e52873b5' 
  AND token = 'bhgTql5ztfFNCeMIlcoQPuZE+WNrMfG7Hi05mjDlXDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}