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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c726812618659b477a7da54f4e5b3c6339fb8266a775a4d6dadb0402f22fef9' 
  AND token = 'G2Dehl8cixxbeMXaw7kuYgPd+L6IrcDTUPQxDuCOzro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}