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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f20e6d2539d1e2882ff2c51d9057ec028ff28137ff97b3bf936dc1356e86d07' 
  AND token = 'M56NYQh4v0Z8zVjgCO1rrtyCWNQSs73S7CnCvOr+JCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}